UCLA Neuroscience Program Ph.D. Admissions Neuroscience Faculty UCLA and Beyond  



Marie-Francoise Chesselet

Email Address:  mchesselet@mednet.ucla.edu

Laboratory Address:
B117 Reed
Work Address:
B114 Reed
Phone Numbers:
(310) 267-1786 Fax
Phone Numbers:
(310) 267-1781 Office

Selected Publications:

Wang Lixin, Fleming Sheila M, Chesselet Marie-Françoise, Taché Yvette Abnormal colonic motility in mice overexpressing human wild-type alpha-synuclein.. Neuroreport. 2008; 19(8): 873-6.
Meredith Gloria E, Sonsalla Patricia K, Chesselet Marie-Francoise Animal models of Parkinson's disease progression.. Acta neuropathologica. 2008; 115(4): 385-98.
Reliene Ramune, Fleming Sheila M, Chesselet Marie-Françoise, Schiestl Robert H Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008; 46(4): 1371-7.
Chesselet Marie-Francoise In vivo alpha-synuclein overexpression in rodents: a useful model of Parkinson's disease?. Experimental neurology. 2008; 209(1): 22-7.
Fleming Sheila M, Tetreault Nicole A, Mulligan Caitlin K, Hutson Ché B, Masliah Eliezer, Chesselet Marie-Françoise Olfactory deficits in mice overexpressing human wildtype alpha-synuclein.. The European journal of neuroscience. 2008; 28(2): 247-56.
Effros Rita B, Austad Steven, Blau Helen, Chesselet Marie-Francoise, Ingram Donald, Johnson Thomas E, Kaeberlein Matt, Lundblad Vicki, McCarter Roger, McElhaney Janet, Saag Michael The biological sciences section program at the 60th Annual Meeting of the Gerontological Society of America.. The journals of gerontology. Series A, Biological sciences and medical sciences. 2008; 63(4): 331-7.
Chesselet MF, Plotkin JL, Wu N, Levine MS. Development of striatal fast-spiking GABAergic interneurons.. Prog Brain Res 2007; 160: 261-72.
Litvan Irene, Chesselet Marie-Francoise, Gasser Thomas, Di Monte Donato A, Parker Davis, Hagg Theo, Hardy John, Jenner Peter, Myers Richard H, Price Donald, Hallett Mark, Langston William J, Lang Anthony E, Halliday Glenda, Rocca Walter, Duyckaerts Charles, Dickson Dennis W, Ben-Shlomo Yoav, Goetz Christopher G, Melamed Eldad The etiopathogenesis of Parkinson disease and suggestions for future research. Part II.. Journal of neuropathology and experimental neurology. 2007; 66(5): 329-36.
Litvan Irene, Halliday Glenda, Hallett Mark, Goetz Christopher G, Rocca Walter, Duyckaerts Charles, Ben-Shlomo Yoav, Dickson Dennis W, Lang Anthony E, Chesselet Marie-Francoise, Langston William J, Di Monte Donato A, Gasser Thomas, Hagg Theo, Hardy John, Jenner Peter, Melamed Eldad, Myers Richard H, Parker Davis, Price Donald L The etiopathogenesis of Parkinson disease and suggestions for future research. Part I.. Journal of neuropathology and experimental neurology. 2007; 66(4): 251-7.
Fleming, SM., Salcedo, J., Hutson, CB., Rockenstein, E., Masliah, E., Levine, MS., Chesselet, MF. Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype alpha-synuclein. Neuroscience 2006; 142: 1245-1253.
Fleming SM, Chesselet MF. Behavioral phenotypes and pharmacology in genetic mouse models of Parkinsonism.. Behav Pharmacol 2006; 17(5-6): 383-91.
Dewing P, Chiang CW, Sinchak K, Sim H, Fernagut PO, Kelly S, Chesselet MF, Micevych PE, Albrecht KH, Harley VR, Vilain E. Direct regulation of adult brain function by the male-specific factor SRY.. Curr Biol 2006; 16(4): 415-20.
Riban Veronique, Chesselet Marie-Françoise Region-specific sprouting of crossed corticofugal fibers after unilateral cortical lesions in adult mice.. Experimental neurology. 2006; 197(2): 451-7.
Hwang, DY Fleming, SM Ardayfio, P Moran-Gates, T Kim, H Tarazi, FI Chesselet, MF Kim, KS 3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease.. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 2005; 25(8): 2132-7.
Chesselet MF. Animal models of neurological disorders.. NeuroRx 2005; 2(3): 395.
Hickey, M.A., Gallant, K., Gross, G., Levine, M.S., and Chesselet, M-F. Early behavioural deficits in R6/2 mice suitable for use in preclinical drug testing.. Neurobiology of Disease 2005; 20: 1-11.
Plotkin, J., Wu, N., Chesselet, M-F, and Levine, M.S. Functional and molecular development of striatal fast-spiking GABAergic interneurons and their cortical inputs. European Journal of Neuroscience 2005; 22: 1097-108.
Fleming, S.M., Fernagut, P-O., Chesselet, M-F. Genetic Mouse Models of Parkinsonism: Strengths and Limitations.. NeuroRx 2005; Vol. 2 : 495-503.
Chesselet, M-F., Fernagut, P-O, Fleming, SM. Parkinson���s disease models: from toxins to genes. Drug Discovery Today: Disease Models 2005; Vol. 2 (No. 4): 299-303.
Fleming, SM Zhu, C Fernagut, PO Mehta, A DiCarlo, CD Seaman, RL Chesselet, MF Behavioral and immunohistochemical effects of chronic intravenous and subcutaneous infusions of varying doses of rotenone.. Experimental neurology. . 2004; 187(2): 418-29.
Fleming, SM Salcedo, J Fernagut, PO Rockenstein, E Masliah, E Levine, MS Chesselet, MF Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.. The Journal of neuroscience : the official journal of the Society for Neuroscience. . 2004; 24(42): 9434-40.
Levine, MS Cepeda, C Hickey, MA Fleming, SM Chesselet, MF Genetic mouse models of Huntington's and Parkinson's diseases: illuminating but imperfect.. Trends in neurosciences. . 2004; 27(11): 691-7.
Zhu, C Vourc'h, P Fernagut, PO Fleming, SM Lacan, S Dicarlo, CD Seaman, RL Chesselet, MF Variable effects of chronic subcutaneous administration of rotenone on striatal histology.. The Journal of comparative neurology. . 2004; 478(4): 418-26.
Menalled, LB Sison, JD Dragatsis, I Zeitlin, S Chesselet, MF Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.. The Journal of comparative neurology. . 2003; 465(1): 11-26.