UCLA Neuroscience Program Ph.D. Admissions Neuroscience Faculty UCLA and Beyond  



Michael Fanselow
Learning, Memory and Emotion

Email Address:  fanselow@psych.ucla.edu
Home Page: http://fanselowlab.psych.ucla.edu/index.html

Work Address:
Franz Hall, #8548
Franz Hall, #8548
Phone Numbers:
(310) 206-5895 Phone Numbers:
(310) 206-3891 Office
(310) 206-3891 Laboratory

Selected Publications:

Sonner James M, Werner David F, Elsen Frank P, Xing Yilei, Liao Mark, Harris R Adron, Harrison Neil L, Fanselow Michael S, Eger Edmond I, Homanics Gregg E Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane.. Anesthesiology. 2007; 106(1): 107-13.
Blaeser Frank, Sanders Matthew J, Truong Nga, Ko Shanelle, Wu Long Jun, Wozniak David F, Fanselow Michael S, Zhuo Min, Chatila Talal A Long-term memory deficits in Pavlovian fear conditioning in Ca2+/calmodulin kinase kinase alpha-deficient mice.. Molecular and cellular biology. 2006; 26(23): 9105-15.
Bryant Camron D, Roberts Kristofer W, Byun Janet S, Fanselow Michael S, Evans Christopher J Morphine analgesic tolerance in 129P3/J and 129S6/SvEv mice.. Pharmacology, biochemistry, and behavior. 2006; 85(4): 769-79.
Landeira-Fernandez J, DeCola Joseph P, Kim Jeansok J, Fanselow Michael S Immediate shock deficit in fear conditioning: effects of shock manipulations.. Behavioral neuroscience. 2006; 120(4): 873-9.
Bryant Camron D, Eitan Shoshana, Sinchak Kevin, Fanselow Michael S, Evans Christopher J NMDA receptor antagonism disrupts the development of morphine analgesic tolerance in male, but not female C57BL/6J mice.. American journal of physiology. Regulatory, integrative and comparative physiology. 2006; 291(2): R315-26.
Wiltgen Brian J, Sanders Matthew J, Anagnostaras Stephan G, Sage Jennifer R, Fanselow Michael S Context fear learning in the absence of the hippocampus.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006; 26(20): 5484-91.
Godsil Bill P, Stefanacci Lisa, Fanselow Michael S Bright light suppresses hyperactivity induced by excitotoxic dorsal hippocampus lesions in the rat.. Behavioral neuroscience. 2005; 119(5): 1339-52.
Schwetz Ines, McRoberts James A, Coutinho Santosh V, Bradesi Sylvie, Gale Greg, Fanselow Michael, Million Mulugeta, Ohning Gordon, Taché Yvette, Plotsky Paul M, Mayer Emeran A Corticotropin-releasing factor receptor 1 mediates acute and delayed stress-induced visceral hyperalgesia in maternally separated Long-Evans rats.. American journal of physiology. Gastrointestinal and liver physiology. 2005; 289(4): G704-12.
Chowdhury Najwa, Quinn Jennifer J, Fanselow Michael S Dorsal hippocampus involvement in trace fear conditioning with long, but not short, trace intervals in mice.. Behavioral neuroscience. 2005; 119(5): 1396-402.
Sonner James M, Cascio Mike, Xing Yilei, Fanselow Michael S, Kralic Jason E, Morrow A Leslie, Korpi Esa R, Hardy Steven, Sloat Brian, Eger Edmond I, Homanics Gregg E Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear.. Molecular pharmacology. 2005; 68(1): 61-8.
Sanders Matthew J, Kieffer Brigitte L, Fanselow Michael S Deletion of the mu opioid receptor results in impaired acquisition of Pavlovian context fear.. Neurobiology of learning and memory. 2005; 84(1): 33-41.
Bradesi Sylvie, Schwetz Ines, Ennes Helena S, Lamy Christophe M R, Ohning Gordon, Fanselow Michael, Pothoulakis Charalabos, McRoberts James A, Mayer Emeran A Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia.. American journal of physiology. Gastrointestinal and liver physiology. 2005; 289(1): G42-53.
Sonner James M, Vissel Bryce, Royle Gordon, Maurer Anya, Gong Diane, Baron Nicole V, Harrison Neil, Fanselow Michael, Eger Edmond I The effect of three inhaled anesthetics in mice harboring mutations in the GluR6 (kainate) receptor gene.. Anesthesia and analgesia. 2005; 101(1): 143-8, table of contents.
Fendt Markus, Fanselow Michael S, Koch Michael Lesions of the dorsal hippocampus block trace fear conditioned potentiation of startle.. Behavioral neuroscience. 2005; 119(3): 834-8.
Sonner James M, Xing Yilei, Zhang Yi, Maurer Anya, Fanselow Michael S, Dutton Robert C, Eger Edmond I Administration of epinephrine does not increase learning of fear to tone in rats anesthetized with isoflurane or desflurane.. Anesthesia and analgesia. 2005; 100(5): 1333-7, table of contents.
de Oca Beatrice M, Fanselow Michael S Amygdala and periaqueductal gray lesions only partially attenuate unconditional defensive responses in rats exposed to a cat.. Integrative physiological and behavioral science : the official journal of the Pavlovian Society. 2005; 39(4): 318-33.
Quinn Jennifer J, Loya Fred, Ma Quang D, Fanselow Michael S Dorsal hippocampus NMDA receptors differentially mediate trace and contextual fear conditioning.. Hippocampus. 2005; 15(5): 665-74.
Rau Vinuta, DeCola Joseph P, Fanselow Michael S Stress-induced enhancement of fear learning: an animal model of posttraumatic stress disorder.. Neuroscience and biobehavioral reviews. 2005; 29(8): 1207-23.
Fanselow Michael S, Poulos Andrew M The neuroscience of mammalian associative learning.. Annual review of psychology. 2005; 56(3): 207-34.
Wiltgen Brian J, Sanders Matthew J, Ferguson Carolyn, Homanics Gregg E, Fanselow Michael S Trace fear conditioning is enhanced in mice lacking the delta subunit of the GABAA receptor.. Learning & memory (Cold Spring Harbor, N.Y.). 2005; 12(3): 327-33.
Godsil Bill P, Fanselow Michael S Light stimulus change evokes an activity response in the rat.. Learning & behavior : a Psychonomic Society publication. 2004; 32(3): 299-310.
Gale Greg D, Anagnostaras Stephan G, Godsil Bill P, Mitchell Shawn, Nozawa Takashi, Sage Jennifer R, Wiltgen Brian, Fanselow Michael S Role of the basolateral amygdala in the storage of fear memories across the adult lifetime of rats.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004; 24(15): 3810-5.
Stote Deborah L, Fanselow Michael S NMDA receptor modulation of incidental learning in Pavlovian context conditioning.. Behavioral neuroscience. 2004; 118(1): 253-7.
Tinsley Matthew R, Quinn Jennifer J, Fanselow Michael S The role of muscarinic and nicotinic cholinergic neurotransmission in aversive conditioning: comparing pavlovian fear conditioning and inhibitory avoidance.. Learning & memory (Cold Spring Harbor, N.Y.). 2004; 11(1): 35-42.
Mayer Emeran A, Fanselow Michael S Dissecting the components of the central response to stress.. Nature neuroscience. 2003; 6(10): 1011-2.
Meffert Mollie K, Chang Jolene M, Wiltgen Brian J, Fanselow Michael S, Baltimore David NF-kappa B functions in synaptic signaling and behavior.. Nature neuroscience. 2003; 6(10): 1072-8.
Han C J, O'Tuathaigh Colm M, van Trigt Laurent, Quinn Jennifer J, Fanselow Michael S, Mongeau Raymond, Koch Christof, Anderson David J Trace but not delay fear conditioning requires attention and the anterior cingulate cortex.. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22): 13087-92.
Sanders Matthew J, Fanselow Michael S Pre-training prevents context fear conditioning deficits produced by hippocampal NMDA receptor blockade.. Neurobiology of learning and memory. 2003; 80(2): 123-9.
Eger Edmond I, Xing Yilei, Pearce Robert, Shafer Steven, Laster Michael J, Zhang Yi, Fanselow Michael S, Sonner James M Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone.. Anesthesia and analgesia. 2003; 96(4): 1010-8, table of contents.
Fanselow Michael S, Gale Greg D The amygdala, fear, and memory.. Annals of the New York Academy of Sciences. 2003; 985(4): 125-34.
Sanders Matthew J, Wiltgen Brian J, Fanselow Michael S The place of the hippocampus in fear conditioning.. European journal of pharmacology. 2003; 463(1-3): 217-23.
González Felisa, Quinn Jennifer J, Fanselow Michael S Differential effects of adding and removing components of a context on the generalization of conditional freezing.. Journal of experimental psychology. Animal behavior processes. 2003; 29(1): 78-83.
Dutton Robert C, Maurer Anya J, Sonner James M, Fanselow Michael S, Laster Michael J, Eger Edmond I Isoflurane causes anterograde but not retrograde amnesia for pavlovian fear conditioning.. Anesthesiology. 2002; 96(5): 1223-9.
Quinn Jennifer J, Oommen Santosh S, Morrison Glenn E, Fanselow Michael S Post-training excitotoxic lesions of the dorsal hippocampus attenuate forward trace, backward trace, and delay fear conditioning in a temporally specific manner.. Hippocampus. 2002; 12(4): 495-504.
Dutton Robert C, Maurer Anya J, Sonner James M, Fanselow Michael S, Laster Michael J, Eger Edmond I Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory.. Anesthesia and analgesia. 2002; 94(3): 631-9; table of contents.
Anagnostaras Stephan G, Gale Greg D, Fanselow Michael S The hippocampus and Pavlovian fear conditioning: reply to Bast et al.. Hippocampus. 2002; 12(4): 561-5.
Research Interest:

My laboratory is primarily interested in the neural basis of learning, memory and motivation. We primarily examine behavior in Pavlovian fear conditioning situations, although we use a variety of other behavioral assays. We use antomical manipulations such as focal brain lesions and site-directed pharmacological infusions in rats and gentically modified mice. Having mapped much of the circuitry involved in fear conditioning we are trying to determine the specific roles that various brain regions contribute to behavior. Additionally, we are very interested at how various regions interact to produce the final behavioral output.