UCLA Neuroscience Program Ph.D. Admissions Neuroscience Faculty UCLA and Beyond  



Elissa Hallem
Olfactory Behavior in Free-living and Parasitic Nematodes

Work Email Address:  ehallem@microbio.ucla.edu
Home Page: http://www.hallemlab.com

Office Address:
BSRB 290D


Phone Numbers:
(310) 825-1778 Office Phone


Selected Publications:

Carrillo Mayra A, Guillermin Manon L, Rengarajan Sophie, Okubo Ryo P, Hallem Elissa A O2-sensing neurons control CO2 response in C. elegans. J Neurosci. 2013; 33(23): 9675-83.
Chaisson Keely E, Hallem Elissa A Chemosensory behaviors of parasites. Trends Parasitol. 2012; 28(10): 427-436.
Dillman Adler R, Guillermin Manon L, Lee Joon Ha, Kim Brian, Sternberg Paul W, Hallem Elissa A Olfaction shapes host-parasite interactions in parasitic nematodes. Proc Natl Acad Sci USA. 2012; 109(35): E2324-E2333.
Guillermin Manon L, Castelletto Michelle L, Hallem Elissa A Differentiation of carbon dioxide-sensing neurons in Caenorhabditis elegans requires the ETS-5 transcription factor. Genetics. 2011; 189(4): 1327-39.
Hallem Elissa A, Dillman Adler R, Hong Annie V, Zhang Yuanjun, Yano Jessica M, Demarco Stephanie F, Sternberg Paul W A sensory code for host seeking in parasitic nematodes. Curr Biol. 2011; 21(5): 377-83.
Hallem Elissa A, Spencer W Clay, McWhirter Rebecca D, Zeller Georg, Henz Stefan R, Ratsch Gunnar, Miller David M, Horvitz H Robert, Sternberg Paul W, Ringstad Niels Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans. Proc Natl Acad Sci USA. 2010; 108: 254-259.
Hallem Elissa A, Sternberg Paul W Acute carbon dioxide avoidance in Caenorhabditis elegans. Proc Natl Acad Sci USA. 2008; 105(23): 8038-43.
Hallem Elissa A, Rengarajan Michelle, Ciche Todd A, Sternberg Paul W Nematodes, bacteria, and flies: a tripartite model for nematode parasitism. Curr Biol. 2007; 17(10): 898-904.
Hallem Elissa A, Carlson John R Coding of odors by a receptor repertoire. Cell. 2006; 125(1): 143-60.
Hallem Elissa A, Dahanukar Anupama, Carlson John R Insect odor and taste receptors. Ann Rev Entomol. 2006; 51(1): 113-35.
Dahanukar Anupama, Hallem Elissa A, Carlson John R Insect chemoreception. Curr Opin Neurobiol. 2005; 15(4): 423-30.
Hallem Elissa A, Carlson John R The odor coding system of Drosophila. Trends Genet. 2004; 20(9): 453-9.
Hallem Elissa A, Ho Michael G, Carlson John R The molecular basis of odor coding in the Drosophila antenna. Cell. 2004; 117(7): 965-79.
Hallem Elissa A, Carlson John R The spatial code for odors is changed by conditioning. Neuron. 2004; 42(3): 359-61.
Hallem Elissa A, Nicole Fox A, Zwiebel Laurence J, Carlson John R Olfaction: mosquito receptor for human-sweat odorant. Nature. 2004; 427(6971): 212-3.
Research Interest:

We are interested in the function and organization of the neural circuitry that mediates odor-driven behaviors in free-living and parasitic animals. We use the free-living model nematode C. elegans as well as both insect-parasitic and mammalian-parasitic nematodes as model systems. The overall goals of our research are to understand the molecular and cellular basis of odor-driven behaviors, and to understand how olfactory systems evolve to enable species-specific behavioral repertoires. We are also interested in how parasitic nematodes use olfactory cues to locate hosts, and how the olfactory systems of parasitic animals differ from those of free-living animals. Please see my lab website for a more detailed description of our research.